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A citação que você faz referência na pergunta é a seguinte:

Doctor: We're not meant to be here. The Tardis draws it's power from the universe, but it's the wrong universe. It's like diesel in a petrol engine.

Mickey: But I've seen it in comics. People go hopping from one alternative world to another. It's easy.

Doctor: Not in the real world. It used to be easy. When the Time Lords kept their eye on everything, you could hop between realities, home in time for tea. Then they died, and took it all with them. The walls of reality closed, the worlds were sealed. Everything became that bit less kind.
_{S02E05 - Rise of the Cybermen (Number 10)}

Uma vez que os Time Lords voltaram, eles foram colocados no fim do universo.

General: Gallifrey is currently positioned at the extreme end of the time continuum, for its own protection. We're at the end of the universe, give or take a star system.

Doctor: I know. I came the long way round.
_{S09E12 - Hell Bent (Number 12)}

O importante a notar é que quando os Time Lords mantiveram seus olhos em tudo você poderia pular entre as realidades. No entanto, uma vez que os Time Lords estão agora no fim do universo, eles não estão de olho nas coisas e, portanto, incapazes de regular (e permitir) saltar entre as realidades.