A aplicabilidade da seção de regulamentos que você cita é encontrada em 14 CFR 259.2 , que afirma:
This part applies to all the flights of a certificated or commuter air carrier if the carrier operates scheduled passenger service or public charter service using any aircraft originally designed to have a passenger capacity of 30 or more seats, and to all flights to and from the U.S. of a foreign carrier if the carrier operates scheduled passenger service or public charter service to and from the U.S. using any aircraft originally designed to have a passenger capacity of 30 or more seats, except as otherwise provided in this part. This part does not apply to foreign carrier charters that operate to and from the United States if no new passengers are picked up in the United States.
A maneira como leio isso é que o regulamento se aplica apenas a voos de operadoras estrangeiras dentro, de ou para os Estados Unidos, mas se aplica a qualquer voo de uma transportadora norte-americana em qualquer parte do mundo.