David Goyer escreveu todos os três filmes de Blade e mais tarde co-criou a série de TV que acontece após Blade: Trindade.
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The TV series takes place after Blade: Trinity since certain events in that film were mentioned in the pilot episode. At the end of Trinity, Blade used the Daystar, a biological weapon that targets and kills vampires specifically. However, the Daystar has not spread as far or as fast as originally designed, as there are still many vampire houses in operation (for example, Marcus, in the second episode, mentions twelve existing vampire Houses to Krista).