Muggle-borns inherit magic from a distant ancestor; they are descended from Squibs who have married Muggles and whose families had lost the knowledge of their wizarding legacy. The magic resurfaces unexpectedly many generations later.
Ele também diz que irmãos mágicos podem nascer como no caso de Collin e Denis Creavey, mas nem sempre, por exemplo, Lily e Petunia.
A explicação na wiki vem, em parte, de um 30 de julho de 2007 webchat com JKR .
J.K. Rowling: Muggleborns will have a witch or wizard somewhere on their family tree, in some cases many, many generations back. The gene re-surfaces in some unexpected places.