Isso soa como " Swan Song ", de Robert R. McCammon. Acontece durante e após um holocausto nuclear.
Do resumo da Wikipedia:
Some people have been afflicted by tumor-like growths which appear only on the head and grow, merging into a fleshy helmet that limits breathing, speaking, and sight. This is commonly called “Job’s Mask”.
Swan acaba liderando os "bons" remanescentes da humanidade e ganha habilidades de cura. Ela viaja com o Josh, um wrestler.