" Seta do Tempo " Partes 1 & 2 [126º e 127º episódios] mostram como Guinan conheceu Picard.
Star Trek: A próxima geração - " Time's Arrow " Parte 2 [6 ª Temporada Episódio 1]
1893 - Data followed by Guinan and Samuel Clemens, is able to follow the alien shapeshifters to the same cavern near San Francisco, where they discover that the aliens traveled to the 19th century to take advantage of a cholera outbreak, draining the life force from humans in infected areas to give the impression that their deaths were the result of an epidemic. In an ensuing struggle over a cane-like device used to open the portal, Data's head is severed from his body and Guinan is injured. As Picard tends to Guinan, the rest of the away team, carrying Data's body which continues to grasp the cane device, follow one of the aliens to the future, with Clemens also following them.
Os eventos descritos acima vêm de Wikipedia e foram aludidos por Guinan em algum momento antes em " Booby Trap " [Temporada 3 Episódio 6] quando Guinan diz: "Um homem careca foi gentil comigo uma vez, quando eu estava sofrendo. "