Os humanos proibiram, religiosamente proibido e temido, computação não humana.
O Jihad Butleriano foi uma guerra épica contra os seres da IA que escravizaram a humanidade. Depois da vitória humana, os humanos proibiram a computação não humana. Assim, várias guildas de computadores humanos (por exemplo, os mentats) se formaram para cultivar a capacidade humana de realizar o tipo de computação que os computadores haviam realizado para eles antes do Jihad.
De Wikipedia
The Butlerian Jihad is an event in the back-story of Frank Herbert's fictional Dune universe. Occurring over 10,000 years before the events chronicled in his 1965 novel Dune, this jihad leads to the outlawing of certain technologies, primarily "thinking machines," a collective term for computers and artificial intelligence of any kind. This prohibition is a key influence on the nature of Herbert's fictional setting.
Do glossário em Dune
JIHAD, BUTLERIAN: (see also Great Revolt) — the crusade against computers, thinking machines, and conscious robots begun in 201 B.G. and concluded in 108 B.G. Its chief commandment remains in the O.C. Bible as "Thou shalt not make a machine in the likeness of a human mind."
De Dune Messiah
"From the days of the Butlerian Jihad when 'thinking machines' had been wiped from most of the universe, computers had inspired distrust."
Em Deus Imperador de Duna, Siona Atreides preside o "Caminho Dourado" de Leto
He knew this experience, but could not change the smallest part of it. No ancestral presences would remain in her consciousness, but she would carry with her forever afterward the clear sights and sounds and smells. The seeking machines would be there, the smell of blood and entrails, the cowering humans in their burrows aware only that they could not escape . . . while all the time the mechanical movement approached, nearer and nearer and nearer ...louder...louder! Everywhere she searched, it would be the same. No escape anywhere.
Se você aceitar as prequelas de Brian Herbert como canhão, então um pequeno grupo de humanos usou uma rede de computadores artificialmente inteligentes chamada Ominus para escravizar a humanidade. Um século depois, Ominus escravizou os humanos que o usaram para isso e escravizou toda a humanidade. Essa escravidão durou nove séculos. Acabou quando Manion Butler incitou os escravos a se revoltarem; Assim, começando o século longo, mas finalmente bem sucedido, Butlerian Jihad.