Antonin Dolohov e Bellatrix Lestrange, respectivamente
Isso não é mencionado nos livros, mas Rowling responde isso em uma entrevista .
Casey Kunze: Who killed Remus and Tonks I think if I knew this, I would get some closure over the very sad, but understandable, death of two of my favorite characters
J.K. Rowling: I'm so sorry! I met a couple on launch night who had come dressed as Lupin and Tonks, and I felt dreadfully guilty as I signed their books!
J.K. Rowling: Remus was killed by Dolohov and Tonks by Bellatrix.
Também declarado em Pottermore (créditos para Gallifreyan):
Remus was no longer in prime fighting condition when he rushed to join the fight. Months of inactivity, using mostly spells of concealment and protection, had blunted his duelling capabilities, and when he ran up against a dueller of Dolohov’s skill, now battle-hardened after months of killing and maiming, his reactions were too slow.