A AvP não é canônica.
De aqui :
the promotional website Weyland Industries retconned the AvP movies from the canon by having Peter Weyland (Guy Pearce, pictured below) as the founder of Weyland Corp, as opposed to having AVP's Charles Bishop Weyland (Lance Henriksen) as the founder of Weyland Industries.
Ridley Scott também não considera o AVP uma parte da franquia Alien .
Bringing Scott back to the franchise he launched all those years ago, Fox did not find a cheerleader for Alien vs Predator.
Damon Lindelof – one of Prometheus's writers – tells a story about raising the issue of Charles Bishop Weyland from AvP with the director (via Crave): "He just sort of looked at me like I had just slapped him in the face."
O AvP era como o Freddy Vs Jason, apenas uma diversão e não uma parte central da história.