Por volta de 2065 e 2070
Aparentemente, o desenvolvimento deles começou por volta de 2065. De 4ed Augmentation (pág. 148):
Cyborgs
Posted By: The Smiling Bandit
Ever since MCT began internally deploying their anthropomorphic Otomo drones back in ’65, folks have commented that things didn’t seem quite right about them.
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OTOMO Product Announcement
Limited Distribution: Full Mitsuhama Subsidiaries Only
Clearance: Secure Sensitive Information (SSI) Only
Draft v.2.1
Since the dawn of optional cybernetic implantation, some have pushed their bodies to the limits. As technology advanced, so did those limits. With the advent of cyborg technology, the bar has been raised to a whole new level. Through our exclusive cerebral containment unit (CCU), a metahuman brain can be conveniently implanted in an entirely cybernetic body.
A data exata em que a produção em massa começou não está clara, mas até 2070, você pode comprar seu próprio cyborg. (página 151):
The preceding fiction introduces Shadowrun players to three different technological breakthroughs that showcase and exploit the cutting edge of augmentation technologies in 2070: biodrones, cyborgs, and cyberzombies.
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A cyborg requires access to delta-grade implants. This essential modification raises the entry price of a CCU to 250,000¥.