Embora se refira a replicadores baseados em transportadores em vez de transportadores per se, aprendemos com o Jornada nas Estrelas: O Manual Técnico da Próxima Geração que quando o material não vivo é transportado, pequenos erros podem ocorrer devido às técnicas de compactação de software usadas para limitar os dados necessários.
Because of the massive amount of computer memory required to store even the simplest object, it is impossible to record each molecule individually. Instead, extensive data compression and averaging techniques are used. Such techniques reduce memory storage required for molecular patterns by factors approaching 2.7 x 109. The resulting single-bit inaccuracies do not significantly impact the quality of most reproduced objects, but preclude the use of replicator technology to re-create living objects. Single-bit molecular errors could have severely detrimental effects on living DNA molecules and neural activity. Cumulative effects have been shown to closely resemble radiation-induced damage.
Você também pode querer notar que a mudança dos transportadores para o modo HD requer um aumento dramático na utilização de energia.
Cargo transporters are generally optimized at the more energy-efficient molecular resolution, but can also be set at quantum resolution if necessary.